By bus: From Havana, it takes about 3 hours and 45 minutes by bus and costs approximately $18 USD/CUC.
Víazul (www.viazul.com) has five daily buses from Havana that stop by Santa Clara and three buses to be back to Havana.
Make sure to book your bus ticket at least a day in advance, the buses frequently sell out a day in advance. You can book your tickets here, but prices are cheaper at the bus stations.
- Havana to Santa Clara: ($18 USD/CUC) –3 hours and 45 minutes
- Trinidad to Santa Clara: ($8 USD/CUC) – 3 hour
If you take a taxi from Havana, it costs approximately $120-150USD/CUC. Also you can order a taxi in advance (online). For more information, click here.
Renting a car is another option. Booking a car rental in Cuba is not easy, so make sure to book a car several weeks, if not months, in advance online.